辐射对小鼠肠道不同解剖区域碱性磷酸酶和葡萄糖-6-磷酸酶的影响。
Radiation effects on alkaline phosphatase and glucose-6-phosphatase in anatomically different regions of mouse intestine.
作者信息
Kaur A, Dubey D P, Gupta G S
出版信息
Strahlentherapie. 1975 Oct;150(4):427-32.
The effect of gamma irradiation on alkaline phosphatase and glucose-6-phosphate has been studied in three anatomically different regions of the small intestine at a surface dose of 400 R. Both the enzymatic activities were shown to be enhanced in duodenum, jejunum and ileum 24 hours after irradiation. The activity of alkaline phosphatase on day 3 tendeed to be low as compared to day 1 post irradiation, but glucose-6-phosphatase continued to rise even after day 3. Maximum rise of glucose-6-phosphatase was observed in the jejunum. On day 9, alkaline phosphatase was diminished below the controls in the whole of intestine, but appeared to be normal on day 10. Glucose-6-phosphatase in duodenum and jejunum on the other hand was comparable to that of control mice; but in ileum, the activity of this enzyme was below the normal values. Physiological significances of these enzymes in intestine has been discussed.
在表面剂量为400伦琴的情况下，研究了γ射线照射对小肠三个解剖学不同区域碱性磷酸酶和葡萄糖-6-磷酸酶的影响。照射后24小时，十二指肠、空肠和回肠的这两种酶活性均显示增强。与照射后第1天相比，第3天碱性磷酸酶活性趋于降低，但葡萄糖-6-磷酸酶甚至在第3天后仍持续升高。空肠中葡萄糖-6-磷酸酶升高幅度最大。第9天，整个肠道的碱性磷酸酶低于对照组，但在第10天似乎正常。另一方面，十二指肠和空肠中的葡萄糖-6-磷酸酶与对照小鼠相当；但在回肠中，这种酶的活性低于正常值。文中讨论了这些酶在肠道中的生理意义。
Zotero 插件