No apparent association between ocular perfusion pressure and visual field damage in normal-tension glaucoma patients.
作者信息
Kurita Naoyuki, Tomidokoro Atsuo, Mayama Chihiro, Aihara Makoto, Araie Makoto
机构信息
Department of Ophthalmology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Department of Ophthalmology, Saitama Red Cross Hospital, Saitama, Japan.
出版信息
Jpn J Ophthalmol. 2006 Nov-Dec;50(6):547-549. doi: 10.1007/s10384-006-0375-4. Epub 2006 Dec 18.
PURPOSE
To investigate the correlation of ocular perfusion pressure (OPP) with general and localized visual field damage in normal-tension glaucoma (NTG) patients.
METHODS
Correlations between OPP, blood pressure, age, intraocular pressure, refractive error, and extent of visual field damage in the eye with the worst mean deviation (MD) were investigated retrospectively in 94 eyes of 94 NTG patients. Visual fields were analyzed statistically with respect to 15 sectors between two age-matched groups of subjects with high or low OPP.
RESULTS
Significant positive correlations were found between OPP and age (P < 0.001), blood pressure and age (P < 0.05), and MD and refractive error (P < 0.01). OPP had no significant correlation with MD or mean sensitivity in the visual field in any of the visual field sectors.
CONCLUSION
OPP and systemic blood pressure have no evident effect on the extent or pattern of visual field damage in NTG.
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