Eggimann P, Chevrolet J-C, Starobinski M, Majno P, Totsch M, Chapuis B, Pittet D
Dept. of Intensive Care Medicine and Burn Center, Centre Hospitalier Universitaire Vaudois, Bugnon 46, CH -1011, Lausanne, Switzerland.
Infection. 2006 Dec;34(6):333-8. doi: 10.1007/s15010-006-5660-0.
Disseminated aspergillosis is thought to occur as a result of vascular invasion from the lungs with subsequent bloodstream dissemination, and portals of entry other than sinuses and/or the respiratory tract remain speculative.
We report two cases of primary aspergillosis in the digestive tract and present a detailed review of eight of the 23 previously-published cases for which detailed data are available.
These ten cases presented with symptoms suggestive of typhlitis, with further peritonitis requiring laparotomy and small bowel segmental resection. All cases were characterized by the absence of pulmonary disease at the time of histologically-confirmed gastrointestinal involvement with vascular invasion by branched Aspergillus hyphae. These cases suggest that the digestive tract may represent a portal of entry for Aspergillus species in immunocompromised patients.
播散性曲霉病被认为是由于肺部血管侵袭并随后经血行播散所致，而鼻窦和/或呼吸道以外的感染途径仍存在推测性。
我们报告了两例消化道原发性曲霉病病例，并对之前发表的23例中有详细数据的8例进行了详细回顾。
这10例患者均表现出提示盲肠炎的症状，进而出现腹膜炎，需要进行剖腹手术和小肠节段切除术。所有病例的特征是，在组织学确诊为胃肠道受累且有分支曲霉菌丝血管侵袭时均无肺部疾病。这些病例表明，消化道可能是免疫功能低下患者曲霉菌的感染途径。
Zotero 插件