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[智利大学临床医院产科小耳畸形和无耳畸形的患病率]

[Prevalence of microtia and anotia at the maternity of the University of Chile Clinical Hospital].

作者信息

Nazer Julio, Lay-Son Guillermo, Cifuentes Lucía

机构信息

Departamento de Obstetricia y Ginecología, Hospital Clínico Universidad de Chile.

出版信息

Rev Med Chil. 2006 Oct;134(10):1295-301. doi: 10.4067/s0034-98872006001000012. Epub 2006 Dec 13.

Abstract

BACKGROUND

Microtia is a congenital defect characterized by disturbances in the size and form of the ear lobe. Anotia corresponds to the absence of the ear lobe.

AIM

To study the prevalence of microtia and anotia at the Maternity of the University of Chile Clinical Hospital.

MATERIAL AND METHODS

Analysis of the database of the Latin American Collaborative Study of Congenital Defects (ECLAMC). All newborns and stillborns with congenital defects are incorporated to this database.

RESULTS

The prevalence of microtia-anotia in the period 1982-2001 was 8.7 per 10,000 born alive. Chilean hospitals have an uniform prevalence of 5.2 per 10,000 born alive. Thirty seven percent presented as isolated malformations and the rest were associated to other defects. Eighty six percent of non isolated cases were part of a syndrome. Sixty eight percent were mild or moderate forms and the rest, severe forms. Two cases were stillborns and two newborns died before hospital discharge.

CONCLUSIONS

The prevalence of microtia in this hospital and in the rest of Chilean hospitals is significantly higher than in the rest of non Chilean hospitals participating in the ECLAMC, that is 4.1 per 10,000 born alive.

摘要

背景

小耳畸形是一种先天性缺陷,其特征为耳垂的大小和形态出现异常。无耳畸形则指耳垂完全缺失。

目的

研究智利大学临床医院妇产科中小耳畸形和无耳畸形的患病率。

材料与方法

分析拉丁美洲先天性缺陷协作研究(ECLAMC)的数据库。所有患有先天性缺陷的新生儿和死产儿均纳入该数据库。

结果

1982年至2001年期间,小耳畸形 - 无耳畸形的患病率为每10,000例活产儿中有8.7例。智利各医院的患病率均一,为每10,000例活产儿中有5.2例。37%表现为孤立性畸形,其余与其他缺陷相关。86%的非孤立性病例属于某种综合征的一部分。68%为轻度或中度形式,其余为重度形式。有2例为死产儿,2例新生儿在出院前死亡。

结论

该医院及智利其他医院中小耳畸形的患病率显著高于参与ECLAMC的其他非智利医院,后者每10,000例活产儿中的患病率为4.1例。

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