Dorsch W, Stuppner H, Wagner H, Gropp M, Demoulin S, Ring J
Children's Hospital, Johannes Gutenberg University, Mainz, FRG.
Int Arch Allergy Appl Immunol. 1991;95(2-3):128-33. doi: 10.1159/000235416.
In the Ayurvedic medicine, Picrorhiza kurroa Royle ex Benth. is used for the treatment of liver and lung diseases. Using different chemical and pharmacological methods, we could identify the phenol glycoside androsin as active compound preventing allergen and platelet-activating factor induced bronchial obstruction in guinea pigs in vivo (10 mg/kg p.o.; 1 h prior to the inhalation challenge). Histamine release from human polymorphonuclear leukocytes in vitro was inhibited by other compounds yet to be identified.
在阿育吠陀医学中，胡黄连（Picrorhiza kurroa Royle ex Benth.）被用于治疗肝脏和肺部疾病。通过不同的化学和药理学方法，我们能够鉴定出酚糖苷androsin是一种活性化合物，它能在体内预防豚鼠因过敏原和血小板活化因子诱导的支气管阻塞（口服10 mg/kg；在吸入激发前1小时）。体外实验中，人多形核白细胞的组胺释放受到其他尚未鉴定的化合物的抑制。
