Ossma Ivan L, Galvis Andrea, Vargas Luis G, Trager Michelle J, Vagefi M Reza, McLeod Stephen D
Department of Ophthalmology, Fundacion Oftalmologica de Santander, Bucaramanga, Colombia.
J Cataract Refract Surg. 2007 Jan;33(1):47-52. doi: 10.1016/j.jcrs.2006.08.049.
To evaluate the clinical outcomes of an accommodating dual-optic intraocular lens (IOL).
Private practice and university centers.
A prospective noncomparative case series with retrospective control comprised 21 patients (26 eyes) scheduled for small-incision extracapsular cataract extraction by phacoemulsification with implantation of the Synchrony dual-optic accommodating IOL (Visiogen) (accommodating IOL group) and 10 patients who had small-incision extracapsular phacoemulsification with implantation of a monofocal, single-optic IOL at least 6 months previously (control group). Patients were examined 1, 3, 6, and 12 months after surgery. Defocus curves in the accommodating IOL group were compared with those in the control group. The main outcome measures were postoperative distance uncorrected and best corrected visual acuity; near uncorrected, distance corrected, and near corrected visual acuity; and accommodative range based on defocus curves.
Twenty-four eyes were available at the 6-month follow-up visit. All eyes had best corrected distance visual acuity of 20/40 or better, and 19 eyes (79%) had an uncorrected distance visual acuity of 20/40 or better. Uncorrected near visual acuity was 20/40 or better in all eyes. With distance correction, 23 eyes (96%) had an acuity of 20/40 or better at near. Defocus curve analysis suggested a mean accommodative range of 3.22 diopters (D) +/- 0.88 (SD) (range 1.00 to 5.00 D) in the accommodating IOL group and 1.65 +/- 0.58 D in the control group (range 1.00 to 2.50 D) (P<.05).
The Synchrony dual-optic IOL shows promise as an option to provide accommodative function in pseudophakic patients.
评估一种可调节双光学区人工晶状体（IOL）的临床效果。
私人诊所和大学中心。
一项前瞻性非对比病例系列研究，设有回顾性对照，包括21例患者（26只眼），计划通过超声乳化白内障吸除术行小切口囊外白内障摘除，并植入同步双光学区可调节IOL（Visiogen）（可调节IOL组），以及10例至少在6个月前行小切口囊外超声乳化白内障吸除术并植入单焦点、单光学区IOL的患者（对照组）。术后1、3、6和12个月对患者进行检查。比较可调节IOL组和对照组的散焦曲线。主要观察指标为术后未矫正和最佳矫正远视力；未矫正近视力、远矫正近视力和近矫正视力；以及基于散焦曲线的调节范围。
6个月随访时24只眼可纳入分析。所有眼的最佳矫正远视力均达到20/40或更好，19只眼（79%）的未矫正远视力为20/40或更好。所有眼的未矫正近视力均为20/40或更好。经远视力矫正后，23只眼（96%）的近视力达到20/40或更好。散焦曲线分析显示，可调节IOL组的平均调节范围为3.22屈光度（D）±0.88（标准差）（范围1.00至5.00 D），对照组为1.65±0.58 D（范围1.00至2.50 D）（P<0.05）。
同步双光学区IOL有望为人工晶状体眼患者提供调节功能。
