Alió Jorge L, Ben-nun Joshua, Rodríguez-Prats José L, Plaza Ana B
Department of Refractive Surgery, Vissum Corp., Instituto Oftalmológico Alicante, Alicante, Spain.
J Cataract Refract Surg. 2009 Oct;35(10):1671-8. doi: 10.1016/j.jcrs.2009.04.043.
To evaluate visual outcomes and accommodative gains 1 year after implantation of the NuLens accommodating intraocular lens (IOL).
Department of Refractive Surgery, Vissum Corp., Alicante, Spain.
This study comprised patients with cataract and atrophic macular degeneration. In each patient, the accommodating IOL was implanted in the eye with the worse visual acuity. At the 12-month follow-up visit, visual acuity and accommodation were measured to determine the efficacy of the IOL. Ultrasound biomicroscopy was used to measure accommodative amplitude.
Ten eyes of 10 patients were evaluated. The mean number of lines patients could read increased from 1.0 preoperatively to 3.8 lines 6 months postoperatively, indicating improvement in uncorrected near visual acuity after IOL implantation. The mean change in cross-section measurements of the IOL was 0.06 mm at 1 month; the value peaked at 3 months (0.21 mm), after which it decreased steadily, becoming stable at 9 months (0.09 mm, which is equivalent to 10.00 diopters [D] of accommodation). Corrected near visual acuity improved slightly (0.7 Jaeger lines) at 12 months, with the best reading distance at 10 cm. These results suggest that the near and distance visual acuities were approximately equal and, therefore, the IOL can produce accommodation of 10.00 D.
The accommodation mechanism of the IOL can produce an ocular power variation of 10.00 D. Near visual acuity improved without compromising distance visual acuity.
评估NuLens可调节人工晶状体（IOL）植入术后1年的视觉效果和调节增益。
西班牙阿利坎特市Vissum公司屈光手术科。
本研究纳入了患有白内障和萎缩性黄斑变性的患者。在每位患者中，将可调节IOL植入视力较差的眼内。在12个月的随访中，测量视力和调节功能以确定IOL的疗效。使用超声生物显微镜测量调节幅度。
对10例患者的10只眼进行了评估。患者术前平均可读行数为1.0行，术后6个月增加到3.8行，表明IOL植入后未矫正近视力有所改善。IOL横截面测量的平均变化在1个月时为0.06 mm；该值在3个月时达到峰值（0.21 mm），此后稳步下降，在9个月时稳定（0.09 mm，相当于10.00屈光度[D]的调节）。矫正近视力在12个月时略有改善（0.7 Jaeger行），最佳阅读距离为10 cm。这些结果表明，近视力和远视力大致相等，因此，该IOL可产生10.00 D的调节。
IOL的调节机制可产生10.00 D的眼屈光力变化。近视力改善而不影响远视力。
