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[煤矿工人鼻黏膜和颊黏膜的细胞学状况]

[The cytological status of the nasal mucosa and the buccal epithelium in coal miners].

作者信息

Bazeliuk L T, Salimbaeva B M

出版信息

Gig Sanit. 2006 Nov-Dec(6):40-2.

PMID:17190056
Abstract

Sixty-four persons were examined. The examination was undertaken to study the cytomophological parameters of the cells of the nasal mucosa and the buccal epithelium in coal miners. Group 1 consisted of 18 donors without contact with industrial dust; Group 2 comprised 24 apparently healthy miners; Group 3 included 22 workers (drift miners) with Stage 1 anthracosilicosis, grade 1 respiratory failure. The patients with Stage 1 anthracosilicosis had noticeably worse morphofunctional characteristics of the epithelium that displayed extensive fields with pronounced structural changes, such as destruction and desquamation of the integumentary epithelium of the nasal mucosa. Nasal mucosal atrophic changes were observed in 50% of the examined miners. Examination of the buccal epithelium in apparently healthy miners (code 0) and in workers with Stage I anthracosilicosis revealed the increased proportion of microfloral (Streptococcus) contamination by 79% and 3.7 times, respectively.

摘要

对64人进行了检查。此次检查旨在研究煤矿工人鼻黏膜和颊黏膜上皮细胞的细胞形态学参数。第1组由18名未接触工业粉尘的捐赠者组成;第2组包括24名看似健康的矿工;第3组包括22名患有一期煤矽肺、一级呼吸衰竭的工人(掘进矿工)。一期煤矽肺患者的上皮细胞形态功能特征明显更差,表现为广泛区域出现明显的结构变化,如鼻黏膜被覆上皮的破坏和脱落。在50%的受检矿工中观察到鼻黏膜萎缩性变化。对看似健康的矿工(代码0)和一期煤矽肺工人的颊黏膜上皮检查发现,微生物(链球菌)污染比例分别增加了79%和3.7倍。

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