微小单孢菌素A，一种从泥炭沼泽森林分离出的微小单孢菌属中获得的新型24元多烯内酰胺大环内酯。

Micromonosporin A, a novel 24-membered polyene lactam macrolide from Micromonospora sp. isolated from peat swamp forest.

作者信息

Thawai Chitti, Kittakoop Prasat, Tanasupawat Somboon, Suwanborirux Khanit, Sriklung Kanlayanee, Thebtaranonth Yodhathai

机构信息

Department of Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.

出版信息

Chem Biodivers. 2004 Apr;1(4):640-5. doi: 10.1002/cbdv.200490055.

DOI:10.1002/cbdv.200490055

PMID:17191875

Abstract

A novel 24-membered polyene lactam macrolide, micromonosporin A (=(3E,5E,7Z,15E,17E,19E,21E)-9,11,13-trihydroxy-14,19,24-trimethyl-1-azacyclotetracosa-3,5,7,15,17,19,21-heptaen-2-one; 1) was isolated from the actinomycete, Micromonospora sp. strain TT1-11, which was isolated from a very acidic peat swamp forest.

摘要

一种新型的24元多烯内酰胺大环内酯类化合物，小单孢菌素A（=(3E,5E,7Z,15E,17E,19E,21E)-9,11,13-三羟基-14,19,24-三甲基-1-氮杂环二十四碳-3,5,7,15,17,19,21-七烯-2-酮；1）是从放线菌小单孢菌属菌株TT1-11中分离得到的，该菌株是从一个酸性很强的泥炭沼泽森林中分离出来的。