Basavaiah Deevi, Reddy Kanumuri Ramesh
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India.
Org Lett. 2007 Jan 4;9(1):57-60. doi: 10.1021/ol062561m.
[reaction: see text] A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1,1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel-Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented.
[反应：见正文] 描述了一种简单的一锅法协议，用于通过四氯化钛介导的1,1-二芳基乙烯与异吲哚酮衍生物之间的反应合成茚并螺异吲哚酮衍生物，该反应通过串联普林斯反应和分子内傅克（PFC）反应构建两个碳-碳键。还提出了这种转化的合理机制。
