Schrek R
Research Service, VA Hospital, Hines, IL.
Med Hypotheses. 1991 Jul;35(3):182-3. doi: 10.1016/0306-9877(91)90230-v.
The hypothesis that interferon may be useful for intractable chronic lymphocytic leukemia (CLL) is based on two incidental findings: first, the similarity in the in vitro radioresistance of the blood lymphocytes of intractable CLL and of hairy cells; secondly, the similarity of the incidence of intractable CLL patients and the incidence of CLL patients who respond to interferon treatment.
干扰素可能对难治性慢性淋巴细胞白血病(CLL)有用这一假说基于两项偶然发现:其一,难治性CLL患者血液淋巴细胞与毛细胞在体外辐射抗性方面的相似性;其二,难治性CLL患者的发病率与对干扰素治疗有反应的CLL患者的发病率相似。