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老年男性的跌倒风险、身体活动及身体机能:男性骨质疏松性骨折研究

Incident fall risk and physical activity and physical performance among older men: the Osteoporotic Fractures in Men Study.

作者信息

Chan Benjamin K S, Marshall Lynn M, Winters Kerri M, Faulkner Kimberly A, Schwartz Ann V, Orwoll Eric S

机构信息

Department of Endocrinology, School of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.

出版信息

Am J Epidemiol. 2007 Mar 15;165(6):696-703. doi: 10.1093/aje/kwk050. Epub 2006 Dec 28.

Abstract

Physical activity and physical performance have been linked to fall risk in the elderly. The authors examined the relation between physical activity and physical performance with incident falls in the Osteoporotic Fractures in Men Study, a large prospective cohort study of 5,995 community-dwelling men in the United States at least 65 years of age. The authors also examined what types of activities are associated with falling. Incident falls between 2000 and 2005 were captured from up to 17 triannual follow-up questionnaires per participant and analyzed with generalized estimating equations. Follow-up averaged 4.5 years. The average risk of falling in the first 4 months of follow-up was 6.6%. The most active quartile had a significantly greater fall risk than did the least active quartile (relative risk = 1.18, 95% confidence interval (CI): 1.07, 1.29). Men with greater leg power and grip strength had significantly reduced fall risk (for highest leg power quartile vs. lowest: relative risk = 0.82, 95% CI: 0.73, 0.92; for highest grip strength quartile vs. lowest: relative risk = 0.76, 95% CI: 0.69, 0.85). Partitioning components of activity showed no association between fall risk and leisure activities but a positive association with household activities (for highest quartile vs.lowest: relative risk = 1.17, 95% CI: 1.07, 1.28).

摘要

身体活动和身体机能与老年人的跌倒风险有关。作者在美国一项针对5995名年龄至少65岁的社区居住男性的大型前瞻性队列研究——男性骨质疏松性骨折研究中,考察了身体活动和身体机能与跌倒事件之间的关系。作者还研究了哪些类型的活动与跌倒有关。通过每位参与者最多17份每三年一次的随访问卷收集2000年至2005年期间的跌倒事件,并使用广义估计方程进行分析。随访平均时长为4.5年。随访前4个月的平均跌倒风险为6.6%。最活跃的四分位数组的跌倒风险显著高于最不活跃的四分位数组(相对风险=1.18,95%置信区间(CI):1.07,1.29)。腿部力量和握力较强的男性跌倒风险显著降低(最高腿部力量四分位数组与最低四分位数组相比:相对风险=0.82,95%CI:0.73,0.92;最高握力四分位数组与最低四分位数组相比:相对风险=0.76,95%CI:0.69,0.85)。对活动组成部分进行划分后发现,跌倒风险与休闲活动之间无关联,但与家务活动呈正相关(最高四分位数组与最低四分位数组相比:相对风险=1.17,95%CI:1.07,1.28)。

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