Lou Emil, Abou-Zeid Nuhad
Department of Medicine, Duke University Medical Center, Durham, NC, USA.
South Med J. 2006 Nov;99(11):1290-1. doi: 10.1097/01.smj.0000232971.27692.0f.
Oculogyric crisis is a neurologic reaction characterized by bilateral dystonic elevation of visual gaze as well as hyperextension of the neck. This reaction is most commonly explained as an adverse effect of numerous medications, such as dopamine receptor blocking agents or neuroleptic medications and traditional antipsychotic or antiemetic drugs, such as prochlorperazine or metoclopramide. A case of oculogyric crisis induced by metoclopramide is described in this paper.
动眼危象是一种神经反应,其特征为双眼凝视的张力障碍性上抬以及颈部过伸。这种反应最常被解释为多种药物的不良反应,比如多巴胺受体阻断剂或抗精神病药物以及传统抗精神病药或止吐药,如氯丙嗪或甲氧氯普胺。本文描述了一例由甲氧氯普胺诱发的动眼危象病例。