Koban Yaran, Ekinci Metin, Cagatay Halil Huseyin, Yazar Zeliha
Department of Ophthalmology, Faculty of Medicine, Kafkas University, Kars, Turkey.
Clin Ophthalmol. 2014 Mar 19;8:567-9. doi: 10.2147/OPTH.S60041. eCollection 2014.
Oculogyric crisis is an acute dystonic reaction of the ocular muscles characterized by bilateral dystonic elevation of visual gaze lasting from seconds to hours. This reaction is most commonly explained as an adverse reaction to drugs such as antiemetics, antipsychotics, antidepressants, antiepileptics, and antimalarials. Although the incidence of metoclopramide-induced acute dystonic reactions has been reported as 25% in children, there have been few published cases on oculogyric crisis in general. It is important to be able to recognize this ocular side effect because, without a thorough patient history, symptoms can be confused with other diseases such as versive seizures, paroxysmal tonic upward gaze, and encephalopathy. In this paper, we report a case of oculogyric crisis induced by metoclopramide.
动眼危象是一种眼肌的急性肌张力障碍反应，其特征为双眼视力凝视的双侧肌张力障碍性抬高，持续数秒至数小时。这种反应最常被解释为对抗呕吐药、抗精神病药、抗抑郁药、抗癫痫药和抗疟药等药物的不良反应。尽管据报道甲氧氯普胺引起的急性肌张力障碍反应在儿童中的发生率为25%，但总体上关于动眼危象的已发表病例很少。能够识别这种眼部副作用很重要，因为如果没有详尽的患者病史，症状可能会与其他疾病混淆，如旋转性癫痫、阵发性强直性上视和脑病。在本文中，我们报告了一例由甲氧氯普胺引起的动眼危象病例。
