Feaver Ashley A, McCune David E, Mysliwiec Angela G, Mysliwiec Vincent
Department of Medicine at Madigan Army Medical Center, Fort Lewis, WA, USA.
South Med J. 2006 Nov;99(11):1292-4. doi: 10.1097/01.smj.0000233182.06540.00.
Twenty medications are associated with drug-induced organizing pneumonia; however, thalidomide is not listed as a potential causative agent. Thalidomide (Thalomid, Celgene Corp., Summit, NJ), an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, is used for the treatment of multiple myeloma. We report a case of organizing pneumonia in a 58-year-old male with multiple myeloma treated with dexamethasone and thalidomide.
有二十种药物与药物性机化性肺炎有关;然而,沙利度胺未被列为潜在的致病因素。沙利度胺(反应停,新泽西州萨默塞特的赛尔基因公司)是一种血管生成抑制剂和免疫调节剂,可降低肿瘤坏死因子-α,用于治疗多发性骨髓瘤。我们报告一例58岁男性多发性骨髓瘤患者,接受地塞米松和沙利度胺治疗后发生机化性肺炎。