Smuck Matthew, Fuller Brian J, Yoder Brian, Huerta Joyce
Department of Physical Medicine and Rehabilitation, The Spine Program, University of Michigan, Suite 202, 325 E. Eisenhower Pkwy, Ann Arbor, MI 48108-0744, USA.
Spine J. 2007 Jan-Feb;7(1):79-82. doi: 10.1016/j.spinee.2006.06.380. Epub 2006 Nov 28.
The incidence of vascular penetration during contrast confirmed fluoroscopically guided transforaminal lumbosacral epidural injections has been reported as 8.9% to 21.3% depending on the level of injection. Recently, intermittent fluoroscopy was shown to miss more than half of the vascular injections observed under live fluoroscopy. The number of misses increased when epidural and vascular contrast flow appeared simultaneously, even if the fluoroscopic image was taken during contrast injection. To date, no studies have documented the incidence of simultaneous epidural and vascular contrast injections. Also, most previous studies of vascular injections did not document use of live fluoroscopy during contrast injection, so the incidence of vascular injections may be higher than reported.
To determine the incidence of simultaneous epidural and vascular contrast injection during lumbosacral transforaminal epidural injections.
STUDY DESIGN/SETTING: A prospective, observational, in vivo, study.
Patients receiving lumbar transforaminal epidural injections at a university-based outpatient spine center.
Incidence of epidural, vascular, and simultaneous epidural and vascular contrast patterns.
One interventional spine physician and three fellows under his direct supervision recorded contrast patterns observed during 191 fluoroscopically guided lumbosacral transforaminal epidural steroid injections with injection of contrast observed under live fluoroscopy.
The incidence of simultaneous epidural and vascular injection during lumbosacral transforaminal epidural injections was 8.9%. The incidence of a vascular injection alone was 4.2%, for a total vascular injection incidence of 13.1%. Subjects with a simultaneous epidural and vascular injection who returned for repeat injection had a statistically significant chance of a repeat simultaneous epidural and vascular injection when the injection was done at the same location. Fluoroscopy time was significantly increased, an average of 8.8 seconds, when a vascular injection was identified. There was no statistically significant correlation between the incidence of simultaneous epidural and vascular injection with subjects' age, sex, level of injection, side of injection, needle gauge, or diagnosis.
Simultaneous epidural and vascular injection is twice as likely to occur as vascular injection alone. Use of intermittent fluoroscopy can miss the transient appearance of the vascular component of these injections, giving the false impression of successful contrast placement. In light of these results, live fluoroscopy is recommended during contrast injection for confirmation of lumbosacral transforaminal epidural injections.
据报道,在透视引导下经椎间孔腰骶部硬膜外注射时血管穿破的发生率为8.9%至21.3%,具体取决于注射节段。最近有研究表明,间歇性透视会漏诊超过一半在实时透视下观察到的血管内注射情况。当硬膜外和血管内造影剂同时流动时,漏诊数量会增加,即使在注射造影剂期间拍摄了透视图像。迄今为止,尚无研究记录硬膜外和血管内造影剂同时注射的发生率。此外,之前大多数关于血管内注射的研究并未记录在注射造影剂期间使用实时透视的情况,因此血管内注射的实际发生率可能高于报道。
确定腰骶部经椎间孔硬膜外注射期间硬膜外和血管内造影剂同时注射的发生率。
研究设计/地点:一项前瞻性、观察性、体内研究。
在一所大学门诊脊柱中心接受腰椎经椎间孔硬膜外注射的患者。
硬膜外、血管内以及硬膜外和血管内造影剂同时出现的发生率。
一名介入脊柱医生及其直接指导下的三名研究员记录了在191例透视引导下的腰骶部经椎间孔硬膜外类固醇注射过程中观察到的造影剂情况,注射过程在实时透视下进行。
腰骶部经椎间孔硬膜外注射期间硬膜外和血管内同时注射的发生率为8.9%。单纯血管内注射的发生率为4.2%,血管内注射的总发生率为13.1%。硬膜外和血管内同时注射的患者再次进行注射时,如果在同一位置注射,再次出现硬膜外和血管内同时注射的可能性具有统计学意义。当识别出血管内注射时,透视时间显著增加,平均增加8.8秒。硬膜外和血管内同时注射的发生率与患者的年龄、性别、注射节段、注射侧、针规格或诊断之间无统计学显著相关性。
硬膜外和血管内同时注射的发生率是单纯血管内注射的两倍。使用间歇性透视可能会漏诊这些注射中血管部分的短暂出现,从而给人一种造影剂成功注入的错误印象。鉴于这些结果,建议在注射造影剂期间使用实时透视以确认腰骶部经椎间孔硬膜外注射。