健康的被动吸烟者肺泡通透性增加。
Healthy passive cigarette smokers have increased pulmonary alveolar permeability.
作者信息
Beadsmoore Clare, Cheow Heok K, Szczepura Katherine, Ruparelia Prina, Peters A Michael
机构信息
Department of Nuclear Medicine, Addenbrooke's Hospital, Cambridge, UK.
出版信息
Nucl Med Commun. 2007 Feb;28(2):75-7. doi: 10.1097/MNM.0b013e328013eb1e.
QUESTION
Does passive smoking have a measurable effect on lung function in otherwise healthy subjects? There is current interest concerning passive smoking but no objective evidence showing that it has any impact on lung function.
METHODS
The pulmonary clearance rate of (99m)Tc-DTPA was measured in 21 healthy volunteers after inhalation as a radio-aerosol and compared between healthy cigarette smokers, passive smokers and non-smokers. All volunteers had normal lung function.
RESULTS
Clearance half-times in healthy passive smokers (n=5) were longer than in healthy smokers (n=6) but clearly shorter compared with healthy non-smokers (n=10) with respective mean values of 45.2 (SD 8.3), 24.3 (8.6) and 80.3 (20) min.
CONCLUSION
Passive smoking has a functional impact on the lung blood/gas barrier.
问题
被动吸烟对其他方面健康的受试者的肺功能有可测量的影响吗？目前人们对被动吸烟很关注，但没有客观证据表明其对肺功能有任何影响。
方法
对21名健康志愿者吸入放射性气溶胶（99m）Tc-DTPA后的肺清除率进行测量，并在健康吸烟者、被动吸烟者和非吸烟者之间进行比较。所有志愿者的肺功能均正常。
结果
健康被动吸烟者（n = 5）的清除半衰期比健康吸烟者（n = 6）长，但与健康非吸烟者（n = 10）相比明显较短，其各自的平均值分别为45.2（标准差8.3）、24.3（8.6）和80.3（20）分钟。
结论
被动吸烟对肺气血屏障有功能性影响。
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