Bernardczyk-Meller J, Wasilewicz R, Pecold-Stepniewska H, Wasiewicz-Rager J
Universitäts-Augenklinik Poznan-Polen.
Klin Monbl Augenheilkd. 2006 Dec;223(12):993-6. doi: 10.1055/s-2006-927155.
It has been reported that the presence of optic disc drusen is mostly not associated with a reduction in function of the visual organ. At present by using more precise diagnostic tools it is possible to find more pathology. The aim of the study was to evaluate changes in peripapillar RNFL thickness and VEP parameters in a group of patients at the Department of Ophthalmology in Poznań, with diagnosed visible idiopathic optic disc drusen.
We have reviewed the medical records of 7 patients (5 women and 2 men) age range 43 - 61 years, mean age 51 years, with idiopathic visible optic disc drusen confirmed by ultrasound B scan. RNFL were measured with use of an OCT system (Stratus, Zeiss): fast RNFL thickness = 3.4. VEP were evaluated with use of a 60 pattern.
In all patients OCT has shown a thinnig of peripapillar retinal nerve fiber layer. The lowest values were found in the superior and inferior quadrants. In 9 eyes we recorded VEPs with prolonged latency P100 from 117.2 - 135.8 msec, with a small reduction of the P100 amplitude.
Idiopathic visible optic disc drusen are associated with changes in peripapillar RNFL thickness, especially in the superior and inferior quadrants. The anatomic pathology is related to functional abnormalities as confirmed with VEP. Detection of this type of drusen should be an indication to search for possible RNFL and VEP pathologies and to monitor their possible progression.
据报道,视盘玻璃疣的存在大多与视觉器官功能减退无关。目前,通过使用更精确的诊断工具,可以发现更多病变。本研究的目的是评估波兹南眼科门诊一组诊断为可见性特发性视盘玻璃疣患者的视乳头周围视网膜神经纤维层(RNFL)厚度和视觉诱发电位(VEP)参数的变化。
我们回顾了7例患者(5例女性和2例男性)的病历,年龄范围为43 - 61岁,平均年龄51岁,经B超检查确诊为特发性可见性视盘玻璃疣。使用光学相干断层扫描(OCT)系统(蔡司Stratus)测量RNFL:快速RNFL厚度 = 3.4。使用60模式评估VEP。
所有患者的OCT均显示视乳头周围视网膜神经纤维层变薄。上下象限的值最低。在9只眼中,我们记录到VEP的P100潜伏期延长,为117.2 - 135.8毫秒,P100波幅略有降低。
特发性可见性视盘玻璃疣与视乳头周围RNFL厚度变化有关,尤其是上下象限。解剖病理学与VEP证实的功能异常有关。检测到这种类型的玻璃疣应提示寻找可能的RNFL和VEP病变并监测其可能的进展。