Katz Bradley J, Pomeranz Howard D
Department of Ophthalmology and Visual Sciences, the John A. Moran Eye Center, and the Department of Neurology, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.
Am J Ophthalmol. 2006 Feb;141(2):248-253. doi: 10.1016/j.ajo.2005.09.029.
To evaluate the visual field with the use of automated perimetry and to evaluate the retinal nerve fiber layer (RNFL) with optical coherence tomography (OCT) in patients with buried optic nerve drusen (OND).
Observational case control study.
Eyes with buried OND were defined as eyes with ultrasound-proved drusen that were not visible with indirect slit-lamp biomicroscopy. All eyes underwent automated perimetry. Some eyes underwent OCT to evaluate the RNFL.
Fifty-eight eyes of 41 patients with buried OND were evaluated. Three eyes (5%) had inferior arcuate scotomas. The other 55 eyes did not have visual field defects. Twenty-one of the eyes without visual field defects underwent RNFL analysis with OCT. All 21 eyes had normal average RNFL thickness. Some eyes had focal RNFL defects, but it is not clear whether these defects were clinically significant.
Visual field defects are uncommon in eyes with buried OND. Eyes with buried OND may have focal RNFL defects but have normal average RNFL thickness. In patients with buried OND and a visual field defect, consideration should be given to searching for other causes of the defect, especially if the defect is substantial.
使用自动视野计评估埋藏性视神经乳头 drusen（OND）患者的视野，并使用光学相干断层扫描（OCT）评估视网膜神经纤维层（RNFL）。
观察性病例对照研究。
埋藏性 OND 的眼睛定义为经超声证实存在 drusen 但间接裂隙灯生物显微镜检查不可见的眼睛。所有眼睛均接受自动视野计检查。部分眼睛接受 OCT 以评估 RNFL。
对 41 例埋藏性 OND 患者的 58 只眼睛进行了评估。3 只眼睛（5%）有下方弓形暗点。其他 55 只眼睛没有视野缺损。21 只无视野缺损的眼睛接受了 OCT 的 RNFL 分析。所有 21 只眼睛的平均 RNFL 厚度均正常。部分眼睛有局限性 RNFL 缺损，但尚不清楚这些缺损是否具有临床意义。
埋藏性 OND 患者的视野缺损并不常见。埋藏性 OND 患者的眼睛可能有局限性 RNFL 缺损，但平均 RNFL 厚度正常。对于有视野缺损的埋藏性 OND 患者，应考虑寻找其他导致缺损的原因，尤其是当缺损严重时。
