脱氧胞苷的5-卤代类似物作为单纯疱疹病毒在细胞培养中复制的选择性抑制剂以及小鼠颅内单纯疱疹病毒感染的相关研究 - Suppr | 超能文献

5-Halogenated analogs of deoxycytidine as selective inhibitors of the replication of herpes simplex viruses in cell culture and related studies of intracranial herpes simplex virus infections in mice.

作者信息

Greer S, Schildkraut I, Zimmerman T, Kaufman H

出版信息

Ann N Y Acad Sci. 1975 Aug 8;255:359-65. doi: 10.1111/j.1749-6632.1975.tb29243.x.

DOI:10.1111/j.1749-6632.1975.tb29243.x

Abstract

摘要

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1

5-Halogenated analogs of deoxycytidine as selective inhibitors of the replication of herpes simplex viruses in cell culture and related studies of intracranial herpes simplex virus infections in mice.脱氧胞苷的5-卤代类似物作为单纯疱疹病毒在细胞培养中复制的选择性抑制剂以及小鼠颅内单纯疱疹病毒感染的相关研究

Ann N Y Acad Sci. 1975 Aug 8;255:359-65. doi: 10.1111/j.1749-6632.1975.tb29243.x.

2

Incorporation of 5-substituted analogs of deoxycytidine into DNA of herpes simplex virus-infected or - transformed cells without deamination to the thymidine analog.将脱氧胞苷的5-取代类似物掺入单纯疱疹病毒感染或转化细胞的DNA中，而不会脱氨基形成胸苷类似物。

Antimicrob Agents Chemother. 1983 Mar;23(3):465-76. doi: 10.1128/AAC.23.3.465.

3

Enzymatic basis for the selective inhibition of varicella-zoster virus by 5-halogenated analogues of deoxycytidine.脱氧胞苷5-卤代类似物对水痘-带状疱疹病毒选择性抑制的酶学基础。

J Virol. 1976 Nov;20(2):478-86. doi: 10.1128/JVI.20.2.478-486.1976.

4

Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activity.脱氧胞苷在不丧失抗疱疹活性的情况下，选择性拮抗脱氧胞苷5-卤代类似物细胞毒性的能力。

Antimicrob Agents Chemother. 1982 Sep;22(3):431-41. doi: 10.1128/AAC.22.3.431.

5

Synthesis, molecular conformation and activity against herpes simplex virus of (E)-5-(2-bromovinyl)-2'-deoxycytidine analogs.

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6

Selective inhibition of the replication of herpes simplex virus by 5-halogenated analogues of deoxycytidine.

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Herpes simplex virus type 2 induced pyrimidine nucleoside kinase: enzymatic basis for the selective antiherpetic effect of 5-halogenated analogues of deoxycytidine.2型单纯疱疹病毒诱导的嘧啶核苷激酶：脱氧胞苷5-卤代类似物选择性抗疱疹作用的酶学基础。

Biochemistry. 1978 Mar 7;17(5):920-8. doi: 10.1021/bi00598a028.

8

Inhibition of the replication of human cytomegalovirus by bromodeoxycytidine in the absence of detectable increases in bromodeoxycytidine kinase activity.在溴脱氧胞苷激酶活性未检测到明显增加的情况下，溴脱氧胞苷对人巨细胞病毒复制的抑制作用。

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Phosphorylation of 5-bromodeoxycytidine in cells infected with herpes simplex virus.感染单纯疱疹病毒的细胞中5-溴脱氧胞苷的磷酸化作用

Proc Natl Acad Sci U S A. 1973 Dec;70(12):3788-92. doi: 10.1073/pnas.70.12.3788.

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Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA.四氢尿苷特异性地促进脱氧胞苷掺入单纯疱疹病毒DNA中。

J Virol. 1981 Mar;37(3):987-93. doi: 10.1128/JVI.37.3.987-993.1981.

引用本文的文献

1

Incorporation of 5-substituted analogs of deoxycytidine into DNA of herpes simplex virus-infected or - transformed cells without deamination to the thymidine analog.将脱氧胞苷的5-取代类似物掺入单纯疱疹病毒感染或转化细胞的DNA中，而不会脱氨基形成胸苷类似物。

Antimicrob Agents Chemother. 1983 Mar;23(3):465-76. doi: 10.1128/AAC.23.3.465.

2

Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activity.脱氧胞苷在不丧失抗疱疹活性的情况下，选择性拮抗脱氧胞苷5-卤代类似物细胞毒性的能力。

Antimicrob Agents Chemother. 1982 Sep;22(3):431-41. doi: 10.1128/AAC.22.3.431.

3

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.（E）-5-（2-溴乙烯基）-2'-脱氧尿苷：一种高效且选择性的抗疱疹药物。

Proc Natl Acad Sci U S A. 1979 Jun;76(6):2947-51. doi: 10.1073/pnas.76.6.2947.

4

Effect of 9-(2-hydroxyethoxymethyl)guanine on herpesvirus-induced keratitis and iritis in rabbits.9-（2-羟乙氧甲基）鸟嘌呤对兔疱疹病毒性角膜炎和虹膜炎的作用

Antimicrob Agents Chemother. 1978 Dec;14(6):842-5. doi: 10.1128/AAC.14.6.842.