Dinh Thanh L, Veves Aristidis
Division of Podiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Dermatol Ther. 2006 Nov-Dec;19(6):348-55. doi: 10.1111/j.1529-8019.2006.00093.x.
Diabetic ulcers are chronic wounds that are the result of repetitive trauma in the insensate foot. The presence of infection and peripheral vascular disease makes the treatment of these wounds demanding and requires a multidisciplinary approach. The main principles of the management include adherence to the principles of good wound care, such as aggressive debridement of all non-viable tissue, adequate off-loading of pressure, prompt treatment of infection and moist wound dressings. Over the last decade, new therapeutic modalities, including growth factors and living skin equivalents, have been available to the practicing physicians. Judicious use of advanced wound care products may provide the best means of treating these challenging wounds in an efficient and cost-effective way.
糖尿病溃疡是慢性伤口，是感觉迟钝的足部反复创伤的结果。感染和外周血管疾病的存在使得这些伤口的治疗颇具挑战性，需要多学科方法。治疗的主要原则包括坚持良好伤口护理的原则，如积极清除所有无活力组织、充分减轻压力、及时治疗感染以及使用湿性伤口敷料。在过去十年中，包括生长因子和活性皮肤替代物在内的新治疗方法已可供执业医生使用。明智地使用先进的伤口护理产品可能是以高效且具成本效益的方式治疗这些具有挑战性伤口的最佳手段。
