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转移性性腺外生殖细胞肿瘤治疗8年后发生的睾丸精原细胞瘤。

Testicular seminoma occurring 8 years after treatment of a metastatic extragonadal germ cell tumor.

作者信息

Ando Ryosuke, Yasui Takahiro, Tozawa Keiichi, Sasaki Shoichi, Hayashi Yutaro, Kohri Kenjiro

机构信息

Department of Nephro-urology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

出版信息

Int J Urol. 2007 Jan;14(1):85-6. doi: 10.1111/j.1442-2042.2006.01544.x.

DOI:10.1111/j.1442-2042.2006.01544.x
PMID:17199868
Abstract

A 30-year-old man was admitted with a chief complaint of left-sided scrotal enlargement, and was diagnosed as having testicular seminoma after orchiectomy. Eight years earlier, he had been treated with chemotherapy for an extragonadal germ cell tumor, without orchiectomy, leading to complete remission. His histological diagnosis at that time was a germ cell tumor, composed of choriocarcinoma and embryonal carcinoma. He was followed up without testicular biopsy. Routine pretreatment testicular biopsy in patients with extragonadal germ cell tumor is controversial, but regular long-term follow up and information on the risk of developing a metachronous testicular tumor are needed after treatment of extragonadal germ cell tumors, even when there seems to be a partial or complete clinical response.

摘要

一名30岁男性因左侧阴囊肿大为主诉入院,睾丸切除术后被诊断为睾丸精原细胞瘤。八年前,他曾因性腺外生殖细胞肿瘤接受化疗,未行睾丸切除术,化疗后完全缓解。当时他的组织学诊断为生殖细胞肿瘤,由绒毛膜癌和胚胎癌组成。此后未进行睾丸活检进行随访。性腺外生殖细胞肿瘤患者术前常规睾丸活检存在争议,但即使在临床似乎有部分或完全缓解的情况下,性腺外生殖细胞肿瘤治疗后仍需要定期进行长期随访,并了解发生异时性睾丸肿瘤的风险。

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