Tajima Motoshi
Veterinary Teaching Hospital, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.
Jpn J Vet Res. 2006 Nov;54(2-3):129-34.
Genotypes and subgenotypes of bovine viral diarrhea virus (BVDV) field isolates from Japan, Germany and the United States of America (USA) were identified, and the prevalent pattern of BVDV in individual countries was estimated genetically. Subgenotypes were determined based on phylogenetic analyses of nucleotide sequences of a part of the E2-coding gene of BVDV. Forty-five, 61 and 56 BVDV strains were isolated from naturally infected cattle in Japan, Germany and USA, respectively, between 1980 and 2003. The most prevalent BVDV in these three countries was BVDV-1b. The second most prevalent BVDV strains were 1a, 1d and BVDV-2 in Japan, Germany and USA, respectively. The most prevalent subgenotype 1b in each country constructed individual small clusters in the subgenotype 1b branch in the phylogenetic tree. Although cattle and/or cattle products were moving among the three countries as part of international trade, the distribution of BVDV in the field in each country showed long-standing individual patterns.
对来自日本、德国和美国的牛病毒性腹泻病毒（BVDV）野毒株的基因型和亚基因型进行了鉴定，并从遗传学角度估计了BVDV在各个国家的流行模式。基于对BVDV E2编码基因部分核苷酸序列的系统发育分析确定了亚基因型。1980年至2003年间，分别从日本、德国和美国自然感染的牛中分离出45株、61株和56株BVDV毒株。这三个国家中最常见的BVDV是BVDV-1b。在日本、德国和美国，第二常见的BVDV毒株分别是1a、1d和BVDV-2。每个国家最常见的亚基因型1b在系统发育树的亚基因型1b分支中形成了各自的小簇。尽管作为国际贸易的一部分，牛和/或牛产品在这三个国家之间流动，但每个国家野外BVDV的分布呈现出长期的各自模式。
