Rabarijaona L P, Rabe T, Ranaivo L H, Raharimalala L A, Rakotomanana F, Rakotondraibe E M, Ramarosandratana B, Rakotoson J D, Rakotonjanabelo L A, Tafangy P B
Groupe de Recherche sur le Paludisme, Institut Pasteur de Madagascar.
Med Trop (Mars). 2006 Oct;66(5):504-12.
The purpose of this article is to present data on malaria in the central highland plateaux of Madagascar and strategies to improve the national malaria control program. Use of rapid diagnosis strips, early home-based fever management with pre-packaged chloroquine treatment kits and proposed new therapeutic combination based on artemisinine are discussed for management of patients with high suspicion of malaria attack. Preventive measures including alternated targeted and full-house indoor spraying for vector control, use of insecticide-impregnated bednets, implementation of intermittent preventive treatment in risk groups, optimization of the epidemic early detection and warning system using the Lot Quality Assurance Sampling method for epidemiological investigation if the alert threshold is exceeded, and provision of rapid diagnosis strips are presented.
本文旨在介绍马达加斯加中部高原地区疟疾的数据以及改善国家疟疾控制项目的策略。文中讨论了使用快速诊断试纸、利用预包装氯喹治疗试剂盒进行早期家庭发热管理以及基于青蒿素提出的新治疗组合，用于管理高度怀疑疟疾发作的患者。还介绍了预防措施，包括交替进行有针对性的和全屋室内喷洒以控制病媒、使用浸有杀虫剂的蚊帐、对风险群体实施间歇性预防治疗、如果超过警报阈值则使用批质量保证抽样方法进行流行病学调查以优化疫情早期检测和预警系统，以及提供快速诊断试纸。
