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使用患者自我报告评估精神分裂症患者精神病性症状的有效性。

The validity of using patient self-report to assess psychotic symptoms in schizophrenia.

作者信息

Niv Noosha, Cohen Amy N, Mintz Jim, Ventura Joseph, Young Alexander S

机构信息

VA Desert Pacific Mental Illness Research, Education and Clinical Center, West Los Angeles VA, MIRECC, Los Angeles, CA 90073, USA.

出版信息

Schizophr Res. 2007 Feb;90(1-3):245-50. doi: 10.1016/j.schres.2006.11.011. Epub 2007 Jan 3.

DOI:10.1016/j.schres.2006.11.011
PMID:17204397
Abstract

Brief, reliable and valid measures of psychosis can be very useful in both clinical practice and research, and for identifying unmet treatment needs in persons with schizophrenia. This study examines the concurrent validity and receiver operating characteristics of the psychosis scale of the Revised Behavior and Symptom Identification Scale (BASIS-R). The study was conducted with 71 adults with schizophrenia who were randomly sampled from a large mental health clinic. Study participants at the West Los Angeles Veterans Healthcare Center were assessed using the BASIS-R, a subjective, self-report measure, and the UCLA Brief Psychiatric Rating Scale (BPRS), a clinician-rated measure administered by highly trained research staff. The psychosis scale of the BASIS-R shows good concurrent validity with the psychosis items on the BPRS. Using the BPRS as the gold standard for measuring psychosis, receiver operating characteristics suggest that both the weighted and unweighted versions of the BASIS-R psychosis scale adequately identify psychosis that is moderate or greater or severe. The performance of the two versions was similar. Unweighted scores are easier to calculate, and we therefore recommend cutoff scores based on the unweighted BASIS-R. We identified a cutoff score of 0.5 to best detect moderate or greater psychosis, and a cutoff score of 1.0 to best detect severe or extremely severe psychosis. The BASIS-R has potential as an assessment tool and screening instrument in schizophrenia.

摘要

简短、可靠且有效的精神病测量方法在临床实践和研究中都非常有用,并且有助于识别精神分裂症患者未满足的治疗需求。本研究考察了修订版行为与症状识别量表(BASIS-R)中精神病分量表的同时效度和接受者操作特征。该研究对从一家大型心理健康诊所随机抽取的71名成年精神分裂症患者进行。洛杉矶西区退伍军人医疗中心的研究参与者接受了BASIS-R(一种主观的自我报告测量工具)以及由训练有素的研究人员实施的临床医生评定的加州大学洛杉矶分校简易精神病评定量表(BPRS)的评估。BASIS-R的精神病分量表与BPRS上的精神病项目显示出良好的同时效度。以BPRS作为测量精神病的金标准,接受者操作特征表明,BASIS-R精神病分量表的加权版和非加权版都能充分识别中度及以上或重度精神病。两个版本的表现相似。非加权分数更容易计算,因此我们推荐基于非加权BASIS-R的临界值。我们确定临界值为0.5时最能检测出中度及以上精神病,临界值为1.0时最能检测出重度或极重度精神病。BASIS-R有潜力作为精神分裂症的一种评估工具和筛查手段。

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