Department of Rheumatology, University of Medicine and Pharmacy, Cluj-Napoca, Romania.
J Gastrointestin Liver Dis. 2006 Dec;15(4):379-82.
The association of Crohn's disease and ankylosing spondylitis is described in up to 30% of cases. Treatment of both conditions is not an easy task. We present the case of a 53 year old woman, diagnosed with colonic Crohn's disease and ankylosing spondilitis, treated initially with increasing doses of sulphasalazine and moderate dose of corticosteroids, with the persistence of severe gastrointestinal and articular symptoms. She underwent therapy with tumor necrosis factor alpha (TNFalpha) inhibitor infliximab, with a spectacular improvement of symptoms, signs and quality of life.
高达 30%的病例中描述了克罗恩病和强直性脊柱炎之间的关联。治疗这两种疾病都不是一件容易的事。我们介绍了一位 53 岁女性的病例，她被诊断患有结肠克罗恩病和强直性脊柱炎，最初接受了增加剂量的柳氮磺胺吡啶和中等剂量的皮质类固醇治疗，但胃肠道和关节症状仍持续严重。她接受了肿瘤坏死因子-α（TNFalpha）抑制剂英夫利昔单抗治疗，症状、体征和生活质量显著改善。
