[简短通讯：用Sabin-Feldman染料试验对献血者弓形虫抗体的调查]

[Short communication: investigation of Toxoplasma gondii antibodies in blood donors by Sabin-Feldman Dye Test].

作者信息

Yilmaz Gül Ruhsar, Babür Cahit, Kiliç Selçuk, Taylan Ozkan Ayşegül, Beyaz Elif, Karakoç A Esra

机构信息

Ankara Eğitim ve Araqtirma Hastanesi, Infeksiyon Hastaliklan ve Klinik Mikrobiyoloji Kliniği, Ankara.

出版信息

Mikrobiyol Bul. 2006 Oct;40(4):375-81.

PMID:17205696

Abstract

In this study, a serological survey of Toxoplasma gondii infection in healthy blood donors admitted to Blood Center of Ministry of Health, Ankara Training and Research Hospital was carried out. Sera from 390 male and 24 female (ages between 18-59 years) were evaluated by using Sabin Feldman Dye Test (SFDT). Of 414 donors 176 (42.5%) were found positive for T. gondii antibodies. Among the seropositive cases, 106 (25.6%) had 1/16, 40 (9.7%) had 1/64, 28 (6.8%) had 1/256, and two (0.5%) had 1/1024 SFDT titers. The seropositivity rates for females and males were found as 62.5% and 41.3%, respectively, and there was no statistically significant difference (p=0.053). A statistically significant increase was detected in the seropositivity rates with age, 39% being under the age of 40 (18-39 years), 54% over the age of 40 (p<0.01). In conclusion, although it is not necessary to screen the blood donors routinely for T. gondii antibodies, if the transfusion of cellular blood components is planned for immunosuppresive recipients, then those bloods should be tested for T. gondii antibodies.

摘要

在本研究中，对安卡拉培训与研究医院卫生部血液中心收治的健康献血者进行了弓形虫感染的血清学调查。采用Sabin Feldman染色试验（SFDT）对390名男性和24名女性（年龄在18 - 59岁之间）的血清进行了评估。在414名献血者中，发现176人（42.5%）弓形虫抗体呈阳性。在血清阳性病例中，106人（25.6%）的SFDT滴度为1/16，40人（9.7%）为1/64，28人（6.8%）为1/256，2人（0.5%）为1/1024。女性和男性的血清阳性率分别为62.5%和41.3%，差异无统计学意义（p = 0.053）。随着年龄增长，血清阳性率有统计学意义的升高，40岁以下（18 - 39岁）为39%，40岁以上为54%（p < 0.01）。总之，虽然没有必要对献血者常规筛查弓形虫抗体，但如果计划为免疫抑制受者输注细胞血液成分，则应检测这些血液的弓形虫抗体。