Nasri Hamid, Yazdani Mohammad
Shahrekord University of Medical Sciences, Hajar Medical, Educational and Therapeutic Center, Hemodialysis Section, P.O. Box 88155-468 Shahrekord, Iran.
Kardiol Pol. 2006 Dec;64(12):1364-8; discussion 1369-71.
The prevalence of hypertension and lipid disorders is increased in patients with diabetes. The relationship between cholesterol and blood pressure values has not yet been well established in this group of patients.
To assess the correlation between lipid levels and blood pressure values in patients with type 2 diabetes.
The study group consisted of 122 patients (82 females, 40 males, mean age 63+/-10 years) with type 2 diabetes. The mean duration of diabetes was 7.4+/-5.8 years, and hypertension 3.2+/-4.6 years. In all patients glycosylated haemoglobin (HbA1c) and lipid serum concentrations were assessed.
The mean serum LDL-cholesterol was 112+/-37 mg/dl (median: 112 mg/dl) and HDL-cholesterol - 47+/-18 mg/dl (median: 44 mg/dl). A significant inverse correlation between HDL-cholesterol and systolic blood pressure (r=-0.177, p=0.05) as well as a positive correlation between LDL-cholesterol and systolic blood pressure values (r=0.196, p=0.031) were found.
In patients with type 2 diabetes there is a significant relationship between lipid levels and blood pressure values, which suggests an increased susceptibility to vascular disease associated with LDL-cholesterol in these patients.
糖尿病患者中高血压和血脂异常的患病率增加。在这组患者中，胆固醇与血压值之间的关系尚未完全明确。
评估2型糖尿病患者血脂水平与血压值之间的相关性。
研究组由122例2型糖尿病患者组成（82例女性，40例男性，平均年龄63±10岁）。糖尿病平均病程为7.4±5.8年，高血压平均病程为3.2±4.6年。对所有患者评估糖化血红蛋白（HbA1c）和血脂血清浓度。
血清低密度脂蛋白胆固醇平均为112±37mg/dl（中位数：112mg/dl），高密度脂蛋白胆固醇为47±18mg/dl（中位数：44mg/dl）。发现高密度脂蛋白胆固醇与收缩压之间存在显著负相关（r = -0.177，p = 0.05），低密度脂蛋白胆固醇与收缩压值之间存在正相关（r = 0.196，p = 0.031）。
在2型糖尿病患者中，血脂水平与血压值之间存在显著关系，这表明这些患者患与低密度脂蛋白胆固醇相关的血管疾病的易感性增加。
