Jelali Mohamed Ali, Luciani Alain, Kobeiter Hicham, Zafrani Serge, Anglade Marie Christine, Zegai Benhalima, Bachir Dora, Rahmouni Alain
Department of Radiology, Centre Hospitalo-Universitaire Henri Mondor, 51 Avenue du Maréchal de Lattre de Tassigny, 94010 Créteil, France.
Cancer Imaging. 2006 Nov 28;6(1):182-5. doi: 10.1102/1470-7330.2006.0030.
Extramedullary haematopoiesis (EMH) is a reactive mechanism by which blood cells are produced outside of the bone marrow to supplement insufficient production or increased destruction of erythrocytes. EMH is uncommon in sickle cell anaemia (SCA). We report the first case of focal intra-hepatic EMH in SCA depicted on MRI occurring in a 32-year-old woman with homozygote SCA and in view of previously published data, highlight the diagnostic features suggesting a differential diagnosis with other focal liver lesions including infectious, inflammatory or primary liver tumors.
髓外造血（EMH）是一种反应机制，通过该机制在骨髓外产生血细胞，以补充红细胞生成不足或破坏增加的情况。EMH在镰状细胞贫血（SCA）中并不常见。我们报告了首例在MRI上显示的SCA患者肝内局灶性EMH病例，该患者为一名32岁的纯合子SCA女性。鉴于先前发表的数据，强调了提示与其他局灶性肝脏病变（包括感染性、炎症性或原发性肝脏肿瘤）进行鉴别诊断的诊断特征。
