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膀胱扩大术患者的肾移植:相关性与演变

Kidney transplants in patients with bladder augmentation: correlation and evolution.

作者信息

Garat Jose Maria, Caffaratti Jorge, Angerri Oriol, Bujons Anna, Villavicencio Humberto

机构信息

Urology, Fundacio Puigvert, Cartagena, 340-350, Barcelona 08025, Spain.

出版信息

Int Urol Nephrol. 2009;41(1):1-5. doi: 10.1007/s11255-006-9164-8. Epub 2007 Jan 9.

Abstract

OBJECTIVE

To review the literature, analyse the evolution of kidney transplants (KT) in patients with bladder augmentation (BA) and investigate the relation between BA and KT.

MATERIALS AND METHODS

Six patients with a history of severe lower urinary tract dysfunction and BA, received a KT at our Unit between 1993 and 2003. Three had moderate renal failure at the moment of the BA. The remaining three had end stage renal failure.

RESULTS

With a follow-up of 7 years (mean) we have a patient survival of 100% and a graft survival of 83%. No complications occurred between the BA and the KT. The few KT complications were not related to BA.

CONCLUSION

When a bladder dysfunction is present, it should be treated before KT. In noncompliant bladders, BA is the best treatment. This can be done to try to avoid end stage renal failure or only to prepare the lower urinary tract for reception of the transplant. The presence of a BA did not worsen the evolution of the KT.

摘要

目的

回顾文献,分析膀胱扩大术(BA)患者肾移植(KT)的发展历程,并研究BA与KT之间的关系。

材料与方法

1993年至2003年间,6例有严重下尿路功能障碍病史且接受过BA的患者在我院接受了KT。3例在进行BA时患有中度肾衰竭。其余3例为终末期肾衰竭。

结果

平均随访7年,患者生存率为100%,移植肾生存率为83%。BA与KT之间未发生并发症。少数KT并发症与BA无关。

结论

存在膀胱功能障碍时,应在KT前进行治疗。对于顺应性差的膀胱,BA是最佳治疗方法。这样做可以试图避免终末期肾衰竭,或仅为下尿路接受移植做准备。BA的存在并未使KT的发展恶化。

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