Department of Urology, Adana Teaching and Medical Research Center, Baskent University Faculty of Medicine, 01250, Adana, Ankara, Turkey.
Int Urol Nephrol. 2010 Dec;42(4):903-7. doi: 10.1007/s11255-010-9739-2. Epub 2010 May 13.
To evaluate the role of video-urodynamic examination prior to renal transplantation.
Sixty-four kidney transplant recipients were included into the study. All patients underwent video-urodynamic examination and separate uroflowmetry. Results were evaluated based on daily mean amount of urine, duration of chronic renal failure and presence of diabetes mellitus.
Thirty-five (54.6%) patients showed video-urodynamic abnormalities. The mean detrusor capacity was 234 ml, the mean detrusor compliance was 17.5 cm H(2)O/ml, the mean maximum detrusor pressure was 61.9 cm H(2)O and the mean Q (max) was 13.8 ml/s in all patients. Vesicoureteral reflux was detected in 15 (23%) patients. The mean detrusor compliance and detrusor capacity significantly decreased as the daily amount of urine decreased and as the duration of chronic renal failure increased. Also, there was no significant relation between presence of diabetes mellitus and detrusor capacity and detrusor compliance.
Video-urodynamic studies before renal transplantation provide earlier diagnosis of lower tract abnormalities, which are likely to cause graft dysfunction.
评估肾移植前视频尿动力学检查的作用。
纳入 64 例肾移植受者。所有患者均行视频尿动力学检查和单独尿流率检查。根据每日平均尿量、慢性肾衰竭持续时间和糖尿病的存在来评估结果。
35 例(54.6%)患者出现视频尿动力学异常。所有患者的平均逼尿肌容量为 234ml,平均逼尿肌顺应性为 17.5cmH2O/ml,最大逼尿肌压力为 61.9cmH2O,最大尿流率(Q(max))为 13.8ml/s。15 例(23%)患者存在输尿管反流。逼尿肌顺应性和逼尿肌容量随着每日尿量的减少和慢性肾衰竭持续时间的延长而显著降低。此外,糖尿病的存在与逼尿肌容量和顺应性之间无显著关系。
肾移植前的视频尿动力学研究提供了对可能导致移植物功能障碍的下尿路异常的早期诊断。