Liu Yu, Zhang Ning, Chen Yong, Wang Li-Hua
Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China.
Org Lett. 2007 Jan 18;9(2):315-8. doi: 10.1021/ol062816w.
A water-soluble fluorescent zinc sensor which binds strongly to Zn2+ (log K = 12.4) was successfully synthesized under physiological conditions. This sensor exhibits a good fluorescence response to Zn2+ over a wide pH range in water. Under the same conditions, several metal ions commonly present in a physiological environment, such as Na+, K+, Ca2+, Mg2+, Mn2+, Fe2+, and Co2+, showed little interference to the fluorescence response to Zn2+. [structure: see text]
在生理条件下成功合成了一种与Zn2+紧密结合（log K = 12.4）的水溶性荧光锌传感器。该传感器在水中的宽pH范围内对Zn2+表现出良好的荧光响应。在相同条件下，生理环境中常见的几种金属离子，如Na+、K+、Ca2+、Mg2+、Mn2+、Fe2+和Co2+，对Zn2+的荧光响应几乎没有干扰。[结构：见正文]
