Sharma Vijay K, Tsivgoulis Georgios, Lao Annabelle Y, Alexandrov Andrei V
Division of Neurology, National University Hospital, Singapore.
Curr Neurol Neurosci Rep. 2007 Jan;7(1):8-20. doi: 10.1007/s11910-007-0016-4.
Transcranial Doppler ultrasonography (TCD) is the only noninvasive examination method that enables the reliable evaluation of blood flow from the basal intracerebral vessels, adding physiologic information to the anatomic images. TCD is relatively inexpensive, can be performed at bedside, and allows monitoring in acute emergency settings and for prolonged periods with a high temporal resolution, making it ideal for studying dynamic cerebrovascular responses. In acute stroke, TCD is capable of providing rapid information about the hemodynamic status of the cerebral circulation and monitoring recanalization in real-time, with a potential for enhancing tissue plasminogen activator-induced thrombolysis. Extended applications such as emboli monitoring, right-to-left shunt detection, and vasomotor reactivity make TCD an important and valuable tool for evaluating stroke mechanisms, planning and monitoring treatment, and determining prognosis.
经颅多普勒超声检查（TCD）是唯一能够可靠评估颅内基底血管血流的无创检查方法，可为解剖图像增添生理学信息。TCD相对便宜，可在床边进行，能够在急性紧急情况下进行监测，并以高时间分辨率进行长时间监测，使其成为研究动态脑血管反应的理想选择。在急性卒中中，TCD能够快速提供有关脑循环血流动力学状态的信息，并实时监测再通情况，有可能增强组织纤溶酶原激活剂诱导的溶栓效果。栓子监测、右向左分流检测和血管舒缩反应性等扩展应用使TCD成为评估卒中机制、规划和监测治疗以及确定预后的重要且有价值的工具。
