Leaf Alexander
Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Curr Opin Lipidol. 2007 Feb;18(1):31-4. doi: 10.1097/MOL.0b013e328012d61b.
There is now a considerable factual basis from laboratory and clinical trials that omega-3 fatty acids of fish oil will prevent fatal arrhythmias in animals and humans and this is the focus of the review.
Several recent trials in humans have strengthened the evidence that omega-3 fatty acids may prevent arrhythmias although this has not been a uniform finding.
Since there are at present some 400 000 deaths annually in the US alone and millions more worldwide, what has been learned about the antiarrhythmic actions of omega-3 fatty acids has considerable potential public-health benefit.
目前,来自实验室和临床试验的大量事实依据表明,鱼油中的ω-3脂肪酸可预防动物和人类的致命性心律失常,这也是本综述的重点。
近期针对人类的多项试验进一步证实了ω-3脂肪酸可能预防心律失常的证据,尽管这一结果并不一致。
仅在美国,目前每年约有40万人死亡,全球范围内还有数百万人死亡,因此,我们对ω-3脂肪酸抗心律失常作用的了解具有相当大的潜在公共卫生益处。