Loh Alvin, Soman Teesta, Brian Jessica, Bryson Susan E, Roberts Wendy, Szatmari Peter, Smith Isabel M, Zwaigenbaum Lonnie
The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
J Autism Dev Disord. 2007 Jan;37(1):25-36. doi: 10.1007/s10803-006-0333-5. Epub 2007 Jan 12.
This study examined motor behaviors in a longitudinal cohort of infant siblings of children with autism. Stereotypic movements and postures occurring during standardized observational assessments at 12 and 18 months were coded from videotapes. Participants included eight infant siblings later diagnosed with autism spectrum disorder (ASD), a random sample of nine non-diagnosed siblings, and 15 controls. Videos were coded blind to diagnostic group. At 12 and 18 months the ASD group "arm waved" more frequently and at 18 months, one posture ("hands to ears") was more frequently observed in the ASD and non-diagnosed group compared to the controls. Overall, the siblings subsequently diagnosed with ASD and the comparison groups had considerable overlap in their repertoires of stereotyped behaviors.
本研究调查了自闭症儿童的婴儿同胞纵向队列中的运动行为。对12个月和18个月时标准化观察评估期间出现的刻板动作和姿势进行录像编码。参与者包括8名后来被诊断为自闭症谱系障碍（ASD）的婴儿同胞、9名未被诊断的同胞的随机样本以及15名对照。录像编码时对诊断组设盲。在12个月和18个月时，ASD组“挥手”更频繁，在18个月时，与对照组相比，ASD组和未被诊断组中一种姿势（“手到耳朵”）出现得更频繁。总体而言，后来被诊断为ASD的同胞和对照组在刻板行为方面有相当大的重叠。
