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[子宫内膜癌]

[Endometrial carcinoma].

作者信息

Engelhard K

机构信息

Krankenhaus Martha-Maria, Stadenstr. 58, Nürnberg, Deutschland.

出版信息

Radiologe. 2011 Jul;51(7):596-601. doi: 10.1007/s00117-010-2116-4.

Abstract

Magnetic resonance imaging (MRI) is the method of choice in staging endometrial cancer. Using MRI early tumor invasion (stage IA) can be differentiated from a deep tumor growth (stage IB) of the myometrium with reported sensitivities of 85-95%.Tumor invasion of the uterine cervix can be depicted with a sensitivity of 80% and specificity of 96%. In demonstrating lymph node metastases MRI shows a sensitivity of 50%, a specificity of 95% and and accuracy of 90%. These diagnostic criteria are decisive for the choice of therapy procedures. So a simple hysterectomy will be performed in early stage IA disease while an extended surgical procedure with pelvic lymphadenectomy and radiotherapy will be considered in advanced stages IB and II disease. Vaginal ultrasound shows lower values in tumor staging with accuracies of 73-95%. Staging accuracies of computed tomography also show lower results with 61-76%. For planning radiotherapy and detection of cancer recurrence MRI is the most valuable tool.

摘要

磁共振成像(MRI)是子宫内膜癌分期的首选方法。利用MRI,早期肿瘤浸润(IA期)可与肌层深度肿瘤生长(IB期)相鉴别,报告的敏感度为85% - 95%。子宫颈肿瘤浸润的显示敏感度为80%,特异度为96%。在显示淋巴结转移方面,MRI的敏感度为50%,特异度为95%,准确度为90%。这些诊断标准对治疗方案的选择具有决定性作用。因此,IA期早期疾病将施行单纯子宫切除术,而IB期和II期晚期疾病则会考虑采用扩大手术加盆腔淋巴结清扫术及放疗。阴道超声在肿瘤分期中的数值较低,准确度为73% - 95%。计算机断层扫描的分期准确度结果也较低,为61% - 76%。对于放疗计划制定和癌症复发检测,MRI是最有价值的工具。

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