Doane Cynthia J, Lee D Rick, Sleeper Meg M
Alamogordo Primate Facility, Holloman Air Force Base, Alamogordo, New Mexico, USA.
Comp Med. 2006 Dec;56(6):512-8.
Although cardiovascular disease is the leading cause of death in the captive chimpanzee population, little is known about the prevalence and etiology of heart disease in this species. We reviewed the physical exam records of 265 common chimpanzees (Pan troglodytes) for electrocardiogram abnormalities. During the 24-mo period reviewed (August 2003 through August 2005), 34 animals were diagnosed with cardiac arrhythmias consisting of ventricular arrhythmias, supraventricular arrhythmias, conduction disturbances, mixed arrhythmias, and bradycardia. The incidence of cardiac arrhythmia was significantly higher in male animals, chimpanzees 20 to 39 y old, and those with structural heart disease. Incidence of cardiac arrhythmia was not significantly higher in animals with hypertension, hyperlipidemia, or chronic viral infections. During the retrospective period, 7 animals with cardiac arrhythmias died or were euthanized. Mortality was significantly higher in animals with ventricular arrhythmias compared with those without ventricular arrhythmias. We conclude that in the common chimpanzee, age, male gender, and structural heart disease are risk factors for developing cardiac arrhythmias and that ventricular arrhythmias are risk factors for mortality.
尽管心血管疾病是圈养黑猩猩群体中的主要死因，但对于该物种心脏病的患病率和病因却知之甚少。我们查阅了265只普通黑猩猩（黑猩猩属）的体格检查记录，以查找心电图异常情况。在回顾的24个月期间（2003年8月至2005年8月），34只动物被诊断患有心律失常，包括室性心律失常、室上性心律失常、传导障碍、混合性心律失常和心动过缓。雄性动物、20至39岁的黑猩猩以及患有结构性心脏病的黑猩猩心律失常的发生率显著更高。患有高血压、高脂血症或慢性病毒感染的动物心律失常发生率并未显著更高。在回顾期间，7只患有心律失常的动物死亡或被安乐死。与没有室性心律失常的动物相比，患有室性心律失常的动物死亡率显著更高。我们得出结论，在普通黑猩猩中，年龄、雄性性别和结构性心脏病是发生心律失常的危险因素，而室性心律失常是死亡的危险因素。
