Petit Fátima, Vilchez Varinka, Torres Gustavo, Molina Omaira, Dorfman Saúl, Mora Eduardo, Cardozo José
Departamento de Patología, Hospital General del Sur.
Arq Neuropsiquiatr. 2006 Dec;64(4):1043-6. doi: 10.1590/s0004-282x2006000600034.
Primary amebic menigoencephalitis (PAM) is rare. Two cases of PAM in Venezuelan patients are described. Case 1, a 10 year-old male with headache, fever, vomiting. The patient swam in a water reservoir before the onset of his disease. He died during his third hospital day. Case 2, a 23 year-old male with a history of headache, fever, vomiting, drowsiness, and behavioral disturbances. The patient died on his second hospital day. The diagnosis in both cases was PAM due to Naegleria fowleri. Central nervous system infection by free-living amebas should be considered in meningoencephalitides with bacterial-free cerebro-spinal fluid.
原发性阿米巴脑膜脑炎（PAM）较为罕见。本文描述了委内瑞拉患者的两例PAM病例。病例1为一名10岁男性，有头痛、发热、呕吐症状。该患者在发病前曾在一个蓄水池中游泳。他在住院第三天死亡。病例2为一名23岁男性，有头痛、发热、呕吐、嗜睡及行为障碍病史。该患者在住院第二天死亡。两例病例均诊断为福氏耐格里阿米巴所致的PAM。对于脑脊液无菌的脑膜脑炎，应考虑由自由生活阿米巴引起的中枢神经系统感染。
