Uekermann J, Channon S, Winkel K, Schlebusch P, Daum I
Institute of Cognitive Neuroscience, Ruhr-University of Bochum, Bochum, Germany.
Addiction. 2007 Feb;102(2):232-40. doi: 10.1111/j.1360-0443.2006.01656.x.
Alcoholism is associated with cognitive deficits, which have been interpreted in terms of a specific vulnerability of the frontal lobes to the toxic effects of alcohol. While executive functions in alcoholism have been investigated extensively, only little work has been carried out on social cognition. The aim of the present study was to investigate the association between executive functions, theory of mind and humour processing in alcoholism.
DESIGN, SETTING, PARTICIPANTS AND MEASUREMENTS: A comprehensive neuropsychological test battery was administered to 29 alcoholic patients (Alc) and 29 healthy controls (HC). The test battery included measurements of affect, general intellectual abilities, executive functions, humour processing and theory of mind. The two groups were comparable with respect to affective variables, IQ, gender and age.
Group comparisons revealed cognitive as well as affective humour processing deficits of alcoholics in comparison with HC. The observed impairments were related to theory of mind and executive functions. The deficits may contribute to interpersonal problems and are thus of relevance to rehabilitation.
酒精中毒与认知缺陷有关，这已根据额叶对酒精毒性作用的特定易损性来解释。虽然酒精中毒的执行功能已得到广泛研究，但关于社会认知的研究却很少。本研究的目的是调查酒精中毒患者的执行功能、心理理论和幽默加工之间的关联。
设计、地点、参与者和测量方法：对29名酒精中毒患者（Alc）和29名健康对照者（HC）进行了全面的神经心理测试。测试包括情感、一般智力能力、执行功能、幽默加工和心理理论的测量。两组在情感变量、智商、性别和年龄方面具有可比性。
组间比较显示，与健康对照者相比，酒精中毒患者存在认知以及情感幽默加工缺陷。观察到的损伤与心理理论和执行功能有关。这些缺陷可能导致人际问题，因此与康复相关。
