既激活脂肪酸合成又抑制脂肪酸降解的大肠杆菌转录因子。
Escherichia coli transcription factor that both activates fatty acid synthesis and represses fatty acid degradation.
作者信息
Henry M F, Cronan J E
机构信息
Department of Microbiology, University of Illinois, Urbana 61801.
出版信息
J Mol Biol. 1991 Dec 20;222(4):843-9. doi: 10.1016/0022-2836(91)90574-p.
PMID:1722255
Abstract
The fadR gene of Escherichia coli encodes a protein that acts as a negative regulator (repressor) of the inducible beta-oxidation pathway. We report that the FadR protein also functions as a positive transcriptional activator of the fabA gene, which encodes the enzyme introducing the double bond of the unsaturated fatty acids of E. coli.
摘要
大肠杆菌的fadR基因编码一种蛋白质，该蛋白质作为可诱导β-氧化途径的负调控因子（阻遏物）发挥作用。我们报道，FadR蛋白还作为fabA基因的正转录激活因子发挥作用，fabA基因编码引入大肠杆菌不饱和脂肪酸双键的酶。
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