Nihill M R, O'Laughlin M P, Mullins C E
Lillie Frank Abercrombie Section of Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston.
Cathet Cardiovasc Diagn. 1991 Nov;24(3):166-72. doi: 10.1002/ccd.1810240305.
Fourteen patients with pulmonary vascular disease, either primary pulmonary hypertension or the result of cardiac defects, underwent balloon atrial septostomy (BAS) over the period of July 1981 to June 1988 because of symptoms of syncope, fatigue, right heart failure, and cardiac arrest. Ages ranged from 4 mo to 50 yr. Two moribund patients died within 24 h of the septostomy due to severe hypoxemia and unrelieved low cardiac output; three others died 2 wk to 35 mo later; the remaining 9 patients have improved symptomatically and are alive 11 to 96 mo after septostomy. One received a heart and lung transplant 19 mo later. We conclude that, in patients with symptomatic cor pulmonale secondary to pulmonary vascular disease, atrial septostomy can improve symptoms and may serve as a palliative bridge to heart and/or lung transplantation.
1981年7月至1988年6月期间，14例患有肺血管疾病（原发性肺动脉高压或心脏缺陷所致）的患者因晕厥、疲劳、右心衰竭和心脏骤停症状接受了球囊房间隔造口术（BAS）。年龄范围从4个月至50岁。两名濒死患者在造口术后24小时内死于严重低氧血症和未缓解的低心输出量；另外三名患者在2周至35个月后死亡；其余9例患者症状改善，造口术后11至96个月仍存活。其中1例在19个月后接受了心肺移植。我们得出结论，对于继发于肺血管疾病的有症状的肺心病患者，房间隔造口术可改善症状，并可作为心脏和/或肺移植的姑息性桥梁。
