Levy Jaime, Benharroch Daniel, Peled Nehama, Lifshitz Tova
Department of Opthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, Israel.
Can J Ophthalmol. 2006 Dec;41(6):772-4. doi: 10.3129/i06-076.
We present the first case, to our knowledge, of Blastoschizomyces capitatus keratitis and melting in a corneal graft. An 80-year-old man was treated for a large, severe corneal abscess and melting in the corneal graft of his right eye. Medical history was negative for hematologic disorders. Urgent penetrating keratoplasty was performed.
Corneal cultures grew B. capitatus. Systemic fluconazole and systemic and topical amphotericin B treatment were started. Three months after the last operation, no recurrence was observed and the graft remained clear. B. capitatus can rarely cause severe keratitis in patients even in the absence of hematologic disorders.
据我们所知，我们首次报告了头裂殖酵母菌性角膜炎并累及角膜移植片溶解的病例。一名80岁男性因右眼角膜移植片出现大面积严重角膜脓肿及溶解而接受治疗。其病史无血液系统疾病。遂行急诊穿透性角膜移植术。
角膜培养结果显示为头裂殖酵母菌。开始给予全身性氟康唑以及全身性和局部用两性霉素B治疗。最后一次手术后三个月，未见复发，移植片保持透明。即使在没有血液系统疾病的患者中，头裂殖酵母菌也很少引起严重的角膜炎。
