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痤疮与光动力疗法:激光和光源新技术

Acne and PDT: new techniques with lasers and light sources.

作者信息

Gold Michael H

机构信息

Gold Skin Care Center, 2000 Richard Jones Road, Suite 220, Nashville, TN 37215, USA.

出版信息

Lasers Med Sci. 2007 Jun;22(2):67-72. doi: 10.1007/s10103-006-0420-z. Epub 2007 Jan 16.

Abstract

Acne vulgaris is one of the most common dermatologic disorders encountered in everyday practice. Treatment options for this often psychologically scarring disease are numerous and, for many individuals, provide relief from the disorder. However, factors such as antibiotic resistance and slow onset of action from many topical therapies have led researchers to seek out alternative therapies, especially for those suffering from moderate to severe inflammatory acne vulgaris. Lasers and light sources are finding increased usage in the treatment of inflammatory acne vulgaris. Light sources including blue lights and intense pulsed lights are becoming regular additions to routine medical management to enhance the therapeutic response. Finally, photodynamic therapy may change many of the acne vulgaris paradigms, as its place is being defined in the treatment of moderate to severe inflammatory acne vulgaris. More and more clinical trials are showing the effectiveness of 5-aminolevulinic acid and photodynamic therapy in the treatment of moderate to severe inflammatory acne vulgaris.

摘要

寻常痤疮是日常临床实践中最常见的皮肤病之一。对于这种常造成心理创伤的疾病,治疗选择众多,而且对许多患者来说,这些治疗能缓解病情。然而,诸如抗生素耐药性以及许多局部治疗起效缓慢等因素,促使研究人员寻找替代疗法,尤其是针对中重度炎症性寻常痤疮患者。激光和光源在炎症性寻常痤疮的治疗中应用越来越广泛。包括蓝光和强脉冲光在内的光源正逐渐成为常规医疗管理的一部分,以增强治疗效果。最后,光动力疗法可能会改变许多寻常痤疮的治疗模式,因为其在中重度炎症性寻常痤疮治疗中的地位正在得到明确。越来越多的临床试验表明,5-氨基酮戊酸和光动力疗法在治疗中重度炎症性寻常痤疮方面具有有效性。

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