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强肝胶囊治疗非酒精性脂肪肝的临床研究

[Clinical study of treatment nonalcoholic fatty liver with qianggan capsule].

作者信息

Chen Ze-Xiong, Zhang Shi-Jun, Yun Li-Rong

机构信息

The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2006 Oct;31(20):1739-41.

Abstract

OBJECTIVE

To investigate the therapeutic effect of Qianggan capsule on the treatment of nonalcoholic fatty liver.

METHODS

One hundred and twenty-two patients of nonalcoholic fatty liver were randomly divided into two groups, 64 patients in the treated group were treated by Qianggan capsule, 5 granule every time, twice per day and the 58 patients in control group were treated by tiopronin, 0. 2 gram every time, third per day with a therapeutic course of 3 months.

RESULT

Serum levels of ALT and gamma-GT were decreased significantly after the treatment of Qianggan capsule (P <0.05). However, TG levels seemed decreased but have not significant difference after the treatment of Qianggan capsule. The serum level of ALT in control group decreased markedly after treatment (P < 0.05), but no obvious change was seen in gamma-GT and TG in control group after treatment. The total effective rate in the treated group was higher than those in the control group (79.69% vs 62.07%, P < 0.05).

CONCLUSION

Qianggan capsule is an effective recipe in treating nonalcoholic fatty liver.

摘要

目的

探讨强肝胶囊治疗非酒精性脂肪肝的疗效。

方法

将122例非酒精性脂肪肝患者随机分为两组,治疗组64例,口服强肝胶囊,每次5粒,每日2次;对照组58例,口服硫普罗宁,每次0.2克,每日3次。疗程均为3个月。

结果

强肝胶囊治疗后患者血清谷丙转氨酶(ALT)及γ-谷氨酰转肽酶(γ-GT)水平显著下降(P<0.05),甘油三酯(TG)水平虽有下降但差异无统计学意义;对照组治疗后ALT水平显著下降(P<0.05),γ-GT及TG水平无明显变化。治疗组总有效率高于对照组(79.69%比62.07%,P<0.05)。

结论

强肝胶囊是治疗非酒精性脂肪肝的有效方剂。

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