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针刺治疗非酒精性脂肪性肝炎的疗效观察

[Observation on therapeutic effect of acupuncture for treatment of patients with nonalcoholic steatohepatitis].

作者信息

Meng Sheng-xi

机构信息

Department of Digestology, The First Affiliated Hospital of Henan College of TCM, Zhengzhou, China.

出版信息

Zhongguo Zhen Jiu. 2009 Aug;29(8):616-8.

Abstract

OBJECTIVE

To observe the therapeutic effect of acupuncture for treatment of patients with nonalcoholic steatohepatitis.

METHODS

Ninety-eight cases were randomly divided into an acupuncture group (n= 50) and a medicine group (n=48). The acupuncture group was treated with acupuncture at Shenshu (BL 23), Guanyuan (CV 4), Taixi (KI 3), Sanyinjiao (SP 6), etc.; the medicine group was treated with oral administration of Polyene Phosphatidylcholine Capsules. They were treated for 12 weeks. The changes of clinical symptoms, serum enzyme, blood fat and abdominal CT performance were compared between the two groups before and after treatment.

RESULTS

After treatment, alanine aminotransferase (ALT), aspartate aminotransferase (AST), galactosylhydroxylysyl glucosyltransferase (GGT), triglyeride (TG) and total cholesterol (TC) significantly decreased in the acupuncture group (all P<0.01); ALT, AST and GGT significantly decreased in the medicine group (all P<0.01), and there were no significant differences in changes of TG and TC in the medicine group (both P>0.05). After treatment, CT image showed there was significant improvement of liver injury in both groups (both P<0.01), and the improvement of liver injury in the acupuncture group was superior to that in the medicine group (P<0.01).

CONCLUSION

Acupuncture has a significant therapeutic effect on nonalcoholic steatohepatitis.

摘要

目的

观察针刺治疗非酒精性脂肪性肝炎患者的疗效。

方法

98例患者随机分为针刺组(n = 50)和药物组(n = 48)。针刺组取肾俞(BL 23)、关元(CV 4)、太溪(KI 3)、三阴交(SP 6)等穴位针刺治疗;药物组口服多烯磷脂酰胆碱胶囊治疗。两组均治疗12周。比较两组治疗前后临床症状、血清酶、血脂及腹部CT表现的变化。

结果

治疗后,针刺组丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、γ-谷氨酰转肽酶(GGT)、甘油三酯(TG)及总胆固醇(TC)均显著降低(均P < 0.01);药物组ALT、AST及GGT显著降低(均P < 0.01),药物组TG及TC变化差异无统计学意义(均P > 0.05)。治疗后,CT图像显示两组肝损伤均有明显改善(均P < 0.01),且针刺组肝损伤改善程度优于药物组(P < 0.01)。

结论

针刺治疗非酒精性脂肪性肝炎疗效显著。

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