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[荷兰人群结直肠癌筛查:多项试点研究的背景]

[Screening the population for colorectal cancer: the background to a number of pilot studies in the Netherlands].

作者信息

van Rijn A F, Dekker E, Kleibeuker J H

机构信息

Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2006 Dec 16;150(50):2739-44.

Abstract

Colorectal cancer is one of the most common cancers in the Netherlands, where it is now the second most commonly-occurring cancer in terms of both incidence (10,000 new cases each year) and mortality rate (4,400 each year). - In 40% of all cases the disease is diagnosed at a late stage, which is associated with a poor outcome. - Research has shown that screening of the general population for colorectal cancer by means of the faecal occult blood test (FOBT) results in a reduction in mortality of approximately 16%. Whether endoscopic screening will result in a greater reduction in the mortality rate is currently under investigation. - This year, the first pilot study on implementation of screening for colorectal cancer using two different types of FOBT will start in the Netherlands.

摘要

结直肠癌是荷兰最常见的癌症之一,目前在发病率(每年10000例新发病例)和死亡率(每年4400例)方面均为第二大常见癌症。 - 在所有病例中,40%的疾病在晚期被诊断出来,这与不良预后相关。 - 研究表明,通过粪便潜血试验(FOBT)对普通人群进行结直肠癌筛查可使死亡率降低约16%。目前正在研究内镜筛查是否会使死亡率有更大幅度的降低。 - 今年,荷兰将启动第一项关于使用两种不同类型的FOBT进行结直肠癌筛查的试点研究。

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