Rosendahl Karen, Toma Paolo
Department of Imaging, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 3JH, UK.
Eur Radiol. 2007 Aug;17(8):1960-7. doi: 10.1007/s00330-006-0557-y. Epub 2007 Jan 18.
Based on soft evidence that ultrasound screening tends to reduce the rate of late developmental dysplasia of the hip (DDH) and the need for surgical interventions, different screening strategies including universal or selective ultrasound screening have been established in several European countries and centres during the last decade. We performed an extensive search for articles on ultrasound diagnosis of developmental dysplasia of the hip over the last 26 years. A few studies reported an adequate repeatability for the static [Graf, Morin, modified Morin (Terjesen)] and for the combined static/dynamic methods [modified Graf (Rosendahl)], while no such reports were found for the dynamic (Harcke) ultrasound techniques. The effect of newborn ultrasound screening on late DDH have been addressed in two randomised trials (RCTs), both concluding that both selective and universal ultrasound screening tend to reduce the prevalence of subluxed or dislocated DDH, thus without reaching statistical significance. Finally, several observational studies have shown that morphologically normal hips tend to remain normal with or without a co-existing instability, and 97% of sonographically immature hips tend to normalise spontaneously within 3 months. Two studies report on a similar pattern for mildly dysplastic, but stable hips. From the data available we suggest that selective ultrasound screening is worthwhile in areas with a high prevalence of late cases, given a well-organised, high-quality service can be provided.
基于超声筛查倾向于降低晚期发育性髋关节发育不良(DDH)的发生率以及手术干预需求的软证据,在过去十年中,欧洲的几个国家和中心已经建立了不同的筛查策略,包括普遍或选择性超声筛查。我们对过去26年中有关超声诊断发育性髋关节发育不良的文章进行了广泛检索。一些研究报告了静态方法[格拉夫(Graf)、莫林(Morin)、改良莫林(特尔耶森(Terjesen))]以及静态/动态联合方法[改良格拉夫(罗森达尔(Rosendahl))]具有足够的可重复性,而动态(哈克(Harcke))超声技术则未发现此类报告。两项随机试验(RCT)探讨了新生儿超声筛查对晚期DDH的影响,两项试验均得出结论,选择性和普遍性超声筛查都倾向于降低半脱位或脱位DDH的患病率,但未达到统计学显著性。最后,几项观察性研究表明,形态正常的髋关节无论是否存在不稳定,往往都能保持正常,97%超声检查不成熟的髋关节在3个月内往往会自发恢复正常。两项研究报告了轻度发育不良但稳定的髋关节的类似模式。根据现有数据,我们建议,在晚期病例高发地区,如果能够提供组织良好、高质量的服务,选择性超声筛查是值得的。