Grünberg Raik, Nilges Michael, Leckner Johan
CRG, Systems Biology program, Dr Aiguader 88, E-08003 Barcelona, Spain.
Bioinformatics. 2007 Mar 15;23(6):769-70. doi: 10.1093/bioinformatics/btl655. Epub 2007 Jan 18.
Biskit is a modular, object-oriented python library that provides intuitive classes for many typical tasks of structural bioinformatics research. It facilitates the manipulation and analysis of macromolecular structures, protein complexes and molecular dynamics trajectories. At the same time, Biskit offers a software platform for the rapid integration of external programs and new algorithms into complex structural bioinformatics workflows. Calculations are thus often delegated to established programs like Xplor, Amber, Hex, Prosa, Hmmer and Modeller; interfaces to further software can be easily added. Moreover, Biskit simplifies the parallelization of time consuming calculations via PVM (Parallel Virtual Machine).
The latest snapshot of Biskit, documentation and examples are freely available under the GNU General Public License at http://biskit.sf.net (alternate url http://biskit.pasteur.fr).
Biskit是一个模块化的、面向对象的Python库,它为结构生物信息学研究的许多典型任务提供了直观的类。它便于对大分子结构、蛋白质复合物和分子动力学轨迹进行操作和分析。同时,Biskit提供了一个软件平台,用于将外部程序和新算法快速集成到复杂的结构生物信息学工作流程中。因此,计算通常委托给诸如Xplor、Amber、Hex、Prosa、Hmmer和Modeller等既定程序;可以轻松添加到其他软件的接口。此外,Biskit通过并行虚拟机(PVM)简化了耗时计算的并行化。
Biskit的最新快照、文档和示例可在GNU通用公共许可证下从http://biskit.sf.net(备用网址http://biskit.pasteur.fr)免费获取。