Sagar Vivek, Kumar Rajesh, Ganguly Nirmal K, Menon Thangam, Chakraborti Anuradha
Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh, 160012 India.
J Bacteriol. 2007 Apr;189(7):2933-5. doi: 10.1128/JB.01619-06. Epub 2007 Jan 19.
When 100 group A streptococcus isolates were screened, drs, a variant of sic, was identified in emm12 and emm55 isolates. Molecular characterization showed that the drs gene sequence is highly conserved, unlike the sic gene sequence. However, the variation in gene size observed was due to the presence of extra internal repeat sequences.
在对100株A群链球菌分离株进行筛查时,在emm12和emm55分离株中鉴定出了sic的一个变体drs。分子特征分析表明,与sic基因序列不同,drs基因序列高度保守。然而,观察到的基因大小差异是由于存在额外的内部重复序列。