Mohri S, Andoh S
Clinic of Dermatology, Yokohama Sakae Kyosai Hospital, Japan.
J Dermatol. 1991 Jul;18(7):414-9. doi: 10.1111/j.1346-8138.1991.tb03107.x.
An asymptomatic tumor developed on the upper lip of a 63-year-old man. Histologically, the tumor contained glandular and cystic structures forming many branching lumina, and many scattered single cells in an abundant mucoid to chondroid stroma. The tumor was diagnosed as mixed tumor of the skin. Histochemically, the cells composing the tubular structures contained neutral mucopolysaccharides and the stroma, acid mucopolysaccharides. Immunohistochemically, the cells of the glandular and cystic structures showed epithelial and sweat gland differentiation (EMA-, CEA-, BRST-1- and BRST-2-positive), while the cells scattered in the stroma showed a tendency toward myoepithelial differentiation (S-100 protein- and vimentin-positive).
一名63岁男性的上唇出现了一个无症状肿瘤。组织学上，肿瘤包含腺性和囊性结构，形成许多分支管腔，在丰富的黏液样至软骨样基质中有许多散在的单个细胞。该肿瘤被诊断为皮肤混合瘤。组织化学上，构成管状结构的细胞含有中性黏多糖，而基质含有酸性黏多糖。免疫组织化学上，腺性和囊性结构的细胞显示上皮和汗腺分化（EMA、CEA、BRST-1和BRST-2阳性），而散在基质中的细胞显示有肌上皮分化倾向（S-100蛋白和波形蛋白阳性）。
